Researchers have found that most peopleʼs bodies make an enzyme, CYP2A6, that plays a crucial role in eliminating nicotine, the addictive drug in cigarettes, from the body.
Setup
There's an enzyme, CYP2A6, that helps to eliminate nicotine from the body.
Smokers whose bodies make the most common form of CYP2A6 tend to be more frequent smokers than smokers whose bodies make less common forms of CYP2A6.
Here's why -- the faster nicotine is eliminated from your body, the more you crave another cigarette, and
Fill in the Blank
... the most common form of CYP2A6 eliminates nicotine from your body faster than other forms of CYP2A6 or no CYP2A6.
Since we need to loop back to "having the most common form of CYP2A6" and make it explain "smoke more often", we are trying to relate "most common form of CYP2A6" to the trigger we're given here that makes you smoke another cigarette.
Goal
Look for some safely worded version of , and thus the more you crave another cigarette, and thus the more you smoke.
That causal chain would explain why smokers with the most common form of CYP2A6 tend to smoke the most.