A certain gene can be stimulated by chemicals in cigarette smoke, causing lung cells to metabolize the chemicals in a way that makes the cells cancerous.
Statements
We're mainly reading for Conditional, Causal, Mathematical, or Pivot language. There are some causal words in the first sentence: stimulated by / causing
And there's a Yet pivot, suggesting that the correct answer will sound like a safe synthesis of the Pivot idea with what came before.
We have a little Causal Chain: chemicals ⇢ gene ⇢ lung cells metabolize in cig smoke stimulated chems cancerously
Then we have the pivot saying that smokers that don't have this gene stimulated have just as high a risk of developing lung cancer.
Evaluate
This is a puzzling pivot. If some smokers don't have the gene stimulated, then it won't cause their lung cells to metabolize the cigarette chemicals in a cancerous way. So why would they have as high a risk of lung cancer as other smokers do?
It seems like either the elevated risk of the smokers that do have the stimulated gene is negligible, or it sounds like the smokers who don't have their gene stimulated have some other risk factor for lung cancer that's higher than the smokers who do have their gene stimulated (to balance out and end up at the same overall risk of lung cancer).
Goal
Since this is Must Be True and we thought of more than one way to resolve the confusion, neither one of those explanations must be true. So maybe the answer will just say some weak truth that allows for both sides of the pivot to be true.