High cholesterol levels are highly correlated with cardiovascular disease.
Given that ...
High cholesterol is highly correlated with cardiovascular disease.
How can it be that ...
In Limone, each resident has had high cholesterol for many years, but hasn't developed cardiovascular disease.
Evaluate / Goal
We're going to need hear something special or atypical about the residents of Limone that can explain why they're not getting cardiovascular disease, despite their high consumption of cholesterol.