Logical ReasoningDifficulty: Medium

PT131 S3 Q16 Explanation

A common genetic mutation

A free, expert breakdown of this official LSAT Logical Reasoning question.

TopicsNecessary Assumption

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Stimulus

A common genetic mutation that lowers levels of the enzyme cathepsin C severely reduces a person's ability to ward off periodontitis, or gum disease. The enzyme triggers immunological reactions that destroy diseased cells and eliminate infections in the mouth. But researchers are developing ways that happens, we will be able to eliminate periodontitis.

What this question is testing

Necessary Assumption

Your task

Find the assumption the argument requires in order for its conclusion to hold.

Common trap

Answers that would help the argument but aren't strictly required (sufficient, not necessary).

Winning move

Negate each choice — the right one breaks the argument when negated.

Reading along? Open the full official question in LawHub — we show a fragment here and keep the reasoning in our own words.

The question
16.

Which one of the following is an assumption on which the

Answer choices

  1. Too Strong: "only way"12% picked this

    Restoring cathepsin C to normal levels is the only way to

    The author is assuming that this is one way to eliminate periodontitis, but there's no way to support the idea that the author thinks it is the only way. In other wording, she does assume this method is Sufficient. She doesn't assume it's Necessary.

  2. Too Strong4% picked this

    Genetic mutation is the only cause of lowered levels of

    Too Strong: "only cause of low cathepsin C" It wouldn't trouble this author's argument if there were other sources of low cathepsin C, because the solution the researchers devise could presumably also help restore their enzyme to normal levels too.

  3. Too Strong: "soon"2% picked this

    Researchers will soon succeed in finding means of restoring cathepsin C

    There's no timeline on the conclusion / argument. It's just "once we get a solution, then periodontitis will be gone". The author never promises or insinuates that we'll get there soon.

  4. Too Strong11% picked this

    Persons who do not have the genetic mutation that lowers levels of cathepsin C do

    Too Strong: "nobody else gets gum disease" This is pretty tempting, similar to how choice (B) is. When you negate them, they definitely raise doubt about the conclusion. For (B), if there are other ways to get low cathepsin C, then maybe those people would still get gum disease (because maybe the solution researchers devise for mutation-caused low cathepsin C wouldn't work for them). For (D), if there are people without the mutation that do get gum disease, then maybe they would still have gum disease, even in a world where we could restore your cathepsin C levels to normal. However, negating this answer certainly doesn't weaken as much as negating choice (E). With (D), it's possible that people who don't have the mutation but do get gum disease are still getting gum disease from low cathepsin C (something other than genetic mutation causes them to have low cathepsin C). In that case, the solution the researchers devise should be able to help these non-mutation people as well. If this answer were re-written as, "Persons who do not have lower levels of cathepsin C do not get gum disease", it would be correct.

  5. Correct72% picked this

    A person whose cathepsin C level has been restored to normal will not

    Why this is right

    The author was definitely thinking that if we restore the enzyme to normal levels, we'll eliminate their periodontitis. If we negate this answer, it says, "Even once you restore someone's cathepsin C levels to normal, they will still suffer from periodontitis", which would destroy the conclusion.

    Skill tested: Necessary Assumption · how this choice captures the argument's function is the move to repeat next time.

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