Logical Reasoning

PT131 · S3 · Q16 A common genetic mutation

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A common genetic mutation that lowers levels of the enzyme cathepsin C severely reduces a person's ability to ward off periodontitis, or gum disease.

Conclusion

Once we can restore the cathepsin C enzyme to normal levels, we will eliminate periodontitis.

Evidence

When a mutation lower levels of cathepsin C enzyme, it severely increases a person's chances of developing periodontitis (the enzyme would usually assist in the immune response to this gum disease).

Evaluation

The conclusion is so harshly worded ("eliminate periodontitis") that to beat this argument all you need is a line of objection that says, .

The author is not only assuming that restoring normal levels of cathepsin C would successfully prevent this form of periodontitis, he's also assuming that there aren't other sources of periodontitis that would still exist.

Goal

Look for an answer assuming that this solution works, or an answer ruling out the possibility of developing periodontitis through some other means.

16.

Which one of the following is an assumption on which the argument depends?

  1. Restoring cathepsin C to normal

    Too Strong: "only way"

    The author is assuming that this is one way to eliminate periodontitis, but there's no way to support the idea that the author thinks it is the only way. In other wording, she does assume this method is Sufficient. She doesn't assume it's Necessary.

    13% picked this

  2. Genetic mutation is the only

    Too Strong

    Too Strong: "only cause of low cathepsin C" It wouldn't trouble this author's argument if there were other sources of low cathepsin C, because the solution the researchers devise could presumably also help restore their enzyme to normal levels too.

    3% picked this

  3. Researchers will soon succeed in

    Too Strong: "soon"

    There's no timeline on the conclusion / argument. It's just "once we get a solution, then periodontitis will be gone". The author never promises or insinuates that we'll get there soon.

    2% picked this

  4. Persons who do not have

    Too Strong

    Too Strong: "nobody else gets gum disease" This is pretty tempting, similar to how choice (B) is. When you negate them, they definitely raise doubt about the conclusion. For (B), if there are other ways to get low cathepsin C, then maybe those people would still get gum disease (because maybe the solution researchers devise for mutation-caused low cathepsin C wouldn't work for them). For (D), if there are people without the mutation that do get gum disease, then maybe they would still have gum disease, even in a world where we could restore your cathepsin C levels to normal. However, negating this answer certainly doesn't weaken as much as negating choice (E). With (D), it's possible that people who don't have the mutation but do get gum disease are still getting gum disease from low cathepsin C (something other than genetic mutation causes them to have low cathepsin C). In that case, the solution the researchers devise should be able to help these non-mutation people as well. If this answer were re-written as, "Persons who do not have lower levels of cathepsin C do not get gum disease", it would be correct.

    11% picked this

  5. Correct

    A person whose cathepsin C

    Why this is right

    The author was definitely thinking that if we restore the enzyme to normal levels, we'll eliminate their periodontitis. If we negate this answer, it says, "Even once you restore someone's cathepsin C levels to normal, they will still suffer from periodontitis", which would destroy the conclusion.

    Skill tested: Necessary Assumption · how this choice captures the argument's function is the move to repeat next time.

    70% picked this

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