Doctors urge people to reduce their cholesterol levels through dietary changes.
Conclusion
One may need to make more than moderate dietary changes, such as veggie diet.
Evidence
Moderate dietary changes often don't lower your cholesterol levels, and doctors urge people to reduce their cholesterol levels.
Evaluate
The last sentence has a therefore. The word "therefore" always signals a conclusion, but not necessarily the Main Conclusion (and on Role and Main Conclusion questions, they often mess with us and put a "Therefore, [Intermediate Conclusion]." at the end of the paragraph.
What is the support for the conclusion in the last sentence? Why do we need to make more dramatic changes than just a moderate diet?
Because moderate diets don't help with your cholesterol, and doctors urge you to reduce your cholesterol.
Since the other two sentences are support for the third, it looks like the third sentence really is the Main Conclusion.
Goal
They're asking us about the 2nd sentence, which was one of the two Premises, supporting the Conclusion in the 3rd sentence.