Logical ReasoningDifficulty: Medium

PT111 S4 Q22 Explanation

Multiple sclerosis is an autoimmune

A free, expert breakdown of this official LSAT Logical Reasoning question.

TopicsMust be False

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Stimulus

Multiple sclerosis is an autoimmune disease: white blood cells attack the myelin sheath that protects nerve fibers in the spinal cord and brain. Medical science now has a drug that can be used to successfully treat multiple sclerosis, but the path that led medical researchers to this drug was hardly straightforward. Initially, the multiple sclerosis patients tested became dramatically worse. The false step proved to be instructive however.

What this question is testing

Must be False

Your task

Break the argument into its conclusion and evidence, then do exactly what the question stem asks with that structure.

Common trap

Answers that sound relevant to the topic but don't connect to the argument's actual reasoning.

Winning move

Predict what a right answer must do, then test each choice against the conclusion-evidence gap.

Reading along? Open the full official question in LawHub — we show a fragment here and keep the reasoning in our own words.

The question
22.

Which one of the following is LEAST compatible with the results of the

Answer choices

  1. Correct74% picked this

    Gamma interferon stops white blood cells from producing

    Why this is right

    What did the passage say about white blood cells / myelin-destroying compounds? It says in the first sentence that MS is a disease in which white blood cells attack the myelin sheath that protects nerve fibers. If gamma interferon stopped white blood cells from attacking the myelin sheath, then that's essentially code language for the idea that "gamma interferon stops MS". But the results of the study are incompatible with that, since giving MS patients gamma interferon made their MS worse.

    Skill tested: Must be False · how this choice captures the argument's function is the move to repeat next time.

  2. Compatible Out of Scope9% picked this

    Administering gamma interferon to those without multiple sclerosis causes an increase in the number of

    Compatible Out of Scope: people w/o MS The whole paragraph is only about people with MS, so we don't have any ammunition for contradicting some idea about people who don't have MS. This answer would actually fit the overall narrative pretty well, as it turns out. Since MS involves white blood cells doing the damage, then giving someone gamma interferon (which increases white blood cells) should theoretically increase the damage from MS. And that's just what happened! We gave MS patients gamma and the MS got worse.

  3. Compatible6% picked this

    Medical researchers have discovered that the gamma interferon level in the cerebrospinal fluid skyrockets just before and

    This answer seems to align with the results of the study. In the study, the addition of gamma interferon to the body was correlated with MS becoming much worse. In this answer, the presence of gamma interferon is correlated with MS attacks.

  4. Compatible6% picked this

    It has now been established that most multiple sclerosis sufferers do not have

    This actually seems to match the inference we made, so it fits nicely with the passage. The results seemed to suggest that scientists were wrong in their initial guess: looks like MS isn't triggered by chronic viral infections. This answer reinforces that inference.

  5. Compatible5% picked this

    The drug now used to treat multiple sclerosis is known to inhibit the activity

    This makes a lot of sense. Since more gamma interferon made MS worse, it would stand to reason that less gamma interferon would make MS better. Thus, it makes sense that a drug that lowers gamma interferon activity might also reduce MS attacks.

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