Although there are immediate short-term gains in crop yield from a single application of certain hydrocarbon-based pesticides to fields on which they have not been previously used, studies have shown clearly that long-term use gradually depresses crop yield from this initially elevated level.
Given
There are immediate short-term gains in crop yield from a single application of certain hydrocarbon-based pesticides to fields on which they have not been previously used.
Studies have shown clearly that long-term use gradually depresses crop yield from this initially elevated level.
Evaluate
The word "although" indicates a concession, and concessions are typically Opposing Ideas. So the first sentence about immediate short-term gains looks like an idea that the conclusion of the argument will contradict.
“We should conclude that” tells us that whatever fills the blank will be the conclusion, but it also tells us that the statement immediately before this sentence—the statement about long-term use—must be the evidence.
Goal
We're looking for a conclusion about the use of these pesticides that is based on the fact that they gradually decrease crop yields. This conclusion will probably dampen our enthusiasm about the initial short-term gains. For a Most Strongly Supported question, beware of answers that are too strong for the evidence we're given or any answer with a new idea which might be out of scope.