McKinley: A double-blind study, in which neither the patient nor the primary researcher knows whether the patient is being given the drug being tested or a placebo, is the most effective procedure for testing the efficacy of a drug. But we will not be able to perform such a study on this aware of whether the patients are getting the drug or a placebo.
Engle: You cannot draw that conclusion at this point, for you are assuming you know what the study will be.
What this question is testing
McKinley's Argument
McKinley says: we can't do a double-blind test on this drug because the drug's effects on patients will give it away.
Engle's Pushback
Engle replies: hold on, you're jumping ahead — you're assuming you already know what the study would show.
Evaluate
Why would Engle say that? Only if Engle thinks McKinley is talking about effects that haven't been confirmed yet — i.e., the drug's therapeutic effects, the very thing the study is designed to test. If McKinley meant already-known side effects, Engle's "you're assuming the outcome" complaint wouldn't apply, because side effects you already know about don't require running the study to discover.
So Engle is reading McKinley as saying Engle thinks that's premature — we don't know yet whether or how the drug will work.
Goal
Find the answer that says: Engle takes McKinley to be referring to therapeutic effects rather than known side effects.
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